SPIE BiOS 2024

Visit us at the SPIE BiOS on 27.01. & 28.01.2024 in San Francisco at the booth of EXOSENS (8273).

Photonics West 2024

Visit us at the Photonics West from 27.01. – 01.02.2024 in San Francisco at the booth of Omicron (4529).

Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative Analysis

A comprehensive comparison study of wide-field and confocal approaches for single molecule localization microscopy has been published recently. The authors exploit lifetime as a marker to differentiate several chromophores. Surprisingly, LINCam even with a lower quantum efficiency outperforms the confocal method in number of acquired photons per molecule in addition to outstanding signal-to-noise ratio and excellent lifetime accuracy.